Wednesday, December 14, 2016

Buddhists are considered happy






Who would not bear in mind the Dalai Lama with a happy laugh on the face, if one was talking about Buddhism and happiness? It is believed that the serenity of the Buddhists is achieved by regular meditation through positive emotions.

But won’t we find this also in Christianity? The following line was found in the church song "Whoever leaves it to the care of God" [German: "Wer nur den lieben Gott läßt walten"] by Georg Neumarck from the year 1657: "Just keep a little quiet, and be happy in yourself" ["Man halte nur ein wenig stille / und sei doch in sich selbst vergnügt"].

In his 45th sermon "In omnibus requiem quaesivi" [English: In everything I sought rest], Meister Eckehart speaks of rest, silence, tranquility. All creation is in search of rest. Verses of the 24th chapter in the book Jesus Sirach are the basis for this sermon. "With them all I sought a place of rest, ..." (Sirach 24:7) Or: "In the city [Jerusalem] which he loves [God] as well as I, I found rest ..." (Sirach 24:11) This rest can be found in both testaments in many places, such as: "He said, my face will go with you and bring you to rest." (Exodus 33:14) "Better a handful of rest than both fists full of trouble and hardship after wind." (Sirach 4:6) "Come to me, all you troublesome and laden, and I will give you rest, take my yoke upon you, and learn from me, for I am meek and humble of heart, and ye shall find rest for your souls” (Matthew 11:28,29).

Han Shan (寒山) has become known in the West by Gary Snyder. The characters mean "Cold Mountain". He is a vagabond poet of the Tang () period; and so it is not surprising that he was the godfather of Jack Kerouac's "The Dharma Bums". Han Shan wandered through the woods, laughed a lot, meditated in nature, and wrote poems on rocks and trees. He was closely associated with the Guo Qing Monastery / Temple (国清寺). The monastery dates back to the 6th century and still exists today. 300 poems by Han Shan have been handed down - but most Chinese poetry collections have 300 poems! “I am sitting quietly between the cliffs”, he writes in a poem.

The worst things that can happen to nowaday's people are a quiet place and an empty battery of the smartphone. But perhaps one does not need immediate enlightenment, but only a slow allowance of phases of rest. And then your stress falls off and you experience cheerful serenity and nevertheless are amused within yourself.


Possible Problems with Piosimilars


Sorry, I couldn’t resist the temptation. I’d like to talk about possible problems with biosimilars. I’ve just read the article on Medscape by Dr. Jonathan Kaye: “The March of the Biosimilars Continues”. In the U.S. the etanercept biosimilar Erelzi™, the adalimumab biosimilar Amjevita™, and the infliximab biosimilar Inflectra® are approved by the FDA. In Europe we already have more biosimilars: the infliximab biosimilars Remsima®, Inflectra®, and Flixabi®, whereof Remsima® and Inflectra® are bioidenticals. And we have the etanercept biosimilar Benepali®.

One problem will be changing from originator to one and even to a second biosimilar to fulfill biosimilar quota. I think this is a bad idea both for medical and legal reasons.

Another problem arises out of the number of originator biologics (already) and biosimilars. Rituximab biosimilars will follow soon. Have look at the IMS Infographic, there are 23 biosimilars are almost ready to be filed for approval. Rheumatologists will spend quite a lot of time with their patients and assistants or nurses to sort out, which product to use and how to avoid confusing one with the other.

But maybe I see more problems than solutions. And maybe I’d be better off with Padre Pio: “Pray, hope, and don't worry. Worry is useless. ...”


Links:
Bioidenticals - Biosimilars - Biologics – Biomimics -



Monday, December 12, 2016

Not so Wintry on the Southern Hemisphere




Frangipani
A fallen blossom, withering
Still smelling of youth

Jacaranda tree
Flamboyant with blue blossoms
But they fall like we


Blue starlings
Grabbing leftover chips
What a happy spring!

Soon after sunset
All cars must leave Etosha
Wilderness remains

Kalahari below
All is red dust
Just like myself

Southern moon
Shines upside down
Walking downside up

.

Friday, December 9, 2016

FreitagsGedichte / Kurze Gedichte 09.12.2016



Glück
    in allem
UnGlück
Des
Lebens
Bleibt
Doch noch
Das
    Glück
Zu leben

Visionen
    wenn
Aus den
Visionen
Blut
Fließt
Ist
Jeder
    Traum
AusGeträumt

Strick
    möge
Der
Strick
ZeReißen
Den
Man
Um
Deinen
    Hals
GeLegt hat

TaufSchein
    TaufSchein
HochzeitsUrkunde
Verträge
TotenSchein
Aber
Den
Wichtigen
LebensBerechtigungsSchein
Will man
    Mir nicht
AusStellen

Seele
    wie mag
Die Seele
BeSchaffen
Sein?
Ein Stern
Eine
Kugel
Oder
Gar
    Eine zer-
TreTeNe Amöbe

Jetzt
    in jedem
Jetzt
VerMuten
Wir
Ein Morgen
Aber
Manchmal
Ist da
    Wirklich nur
Ein Jetzt

.